Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | GPR183 | P32249 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819236 | 0.92 | GPR183 (0.62) | PKMLMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28819231 | 0.92 | GPR183 (0.62) | PKMLMNAPOLBALDH1A1GPR183 | |
| SCHEMBL28819240 | 0.91 | PKM (0.81) | PKMLMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28819260 | 0.90 | PKM (0.53) | PKMLMNAPOLBALDH1A1GAA | |
| SCHEMBL28819228 | 0.90 | PKM (0.53) | PKMLMNAPOLBALDH1A1GAA | |
| SCHEMBL28819253 | 0.88 | LMNA (0.79) | PKMLMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28819261 | 0.85 | GPR183 (0.52) | PKMLMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28948647 | 0.84 | PKM (0.76) | PKMLMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28819249 | 0.84 | ALDH1A1 (0.58) | PKMLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL28715632 | 0.83 | PKM (0.77) | PKMLMNAPOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634465-A | Sulfonyl piperazine-containing pentadiene ketone derivative and preparation method and application thereof | 贵州大学 | 2022-06-17 | — | — | CN | disclosed |