Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | YAP1 | P46937 | 3/20 | 0.66 |
| ▸ | TEAD4 | Q15561 | 3/20 | 0.66 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 8/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | GPR183 | P32249 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700737 | 0.87 | LMNA (0.69) | ALDH1A1YAP1TEAD4TEAD2PKM | |
| SCHEMBL20323444 | 0.85 | YAP1 (0.84) | ALDH1A1YAP1TEAD4TEAD2PKM | |
| SCHEMBL30754624 | 0.85 | ALDH1A1 (0.69) | ALDH1A1PKML3MBTL1GAAGPR183 | |
| SCHEMBL28819232 | 0.85 | YAP1 (0.66) | ALDH1A1YAP1TEAD4TEAD2PKM | |
| SCHEMBL20300422 | 0.85 | PKM (0.71) | ALDH1A1YAP1TEAD4TEAD2PKM | |
| SCHEMBL28819238 | 0.85 | CNR1 (0.62) | ALDH1A1YAP1TEAD4TEAD2PKM | |
| SCHEMBL28819237 | 0.82 | YAP1 (0.65) | ALDH1A1YAP1TEAD4TEAD2PKM | |
| SCHEMBL28819234 | 0.82 | YAP1 (0.77) | ALDH1A1YAP1TEAD4TEAD2PKM | |
| SCHEMBL28706429 | 0.82 | ALDH1A1 (0.70) | ALDH1A1YAP1TEAD4TEAD2PKM | |
| SCHEMBL23259438 | 0.81 | YAP1 (0.60) | ALDH1A1YAP1TEAD4TEAD2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634465-B | Pentadienone derivative containing sulfonyl piperazine as well as preparation method and application thereof | 贵州大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-114634465-A | Sulfonyl piperazine-containing pentadiene ketone derivative and preparation method and application thereof | 贵州大学 | 2022-06-17 | — | — | CN | disclosed |