Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819670 | 0.88 | HSD17B10 (0.61) | MAPTTP53GAALMNAKDM4E | |
| SCHEMBL28819543 | 0.87 | ALDH1A1 (0.46) | MAPTTP53GAASMN1; SMN2LMNA | |
| SCHEMBL28819621 | 0.87 | PTAFR (0.49) | MAPTSMN1; SMN2LMNAKDM4EHSD17B10 | |
| SCHEMBL28819674 | 0.86 | MCHR1 (0.47) | LMNAKDM4EHSD17B10MCHR1PTAFR | |
| SCHEMBL28819716 | 0.86 | ALDH1A1 (0.47) | MAPTGAASMN1; SMN2LMNAKDM4E | |
| SCHEMBL27747028 | 0.86 | KDM4E (0.46) | MAPTKDM4EHSD17B10PTAFRHTT | |
| SCHEMBL28948669 | 0.86 | KDM4E (0.49) | MAPTLMNAKDM4EHSD17B10PTAFR | |
| SCHEMBL28819703 | 0.85 | NR1H4 (0.53) | MAPTLMNAKDM4EHSD17B10PTAFR | |
| SCHEMBL28819624 | 0.85 | KDM4E (0.46) | MAPTTP53SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL28819587 | 0.85 | KDM4E (0.48) | KDM4EHSD17B10MCHR1PTAFRJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |