Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | PTAFR | P25105 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819670 | 0.88 | HSD17B10 (0.61) | PTAFRKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL28819621 | 0.86 | PTAFR (0.49) | PTAFRKDM4EHSD17B10HTTALDH1A1 | |
| SCHEMBL28819605 | 0.85 | KDM4E (0.51) | PTAFRKDM4EHSD17B10HTTALDH1A1 | |
| SCHEMBL28819716 | 0.85 | ALDH1A1 (0.47) | PTAFRKDM4EHSD17B10HTTALDH1A1 | |
| SCHEMBL28819494 | 0.85 | CASR (0.51) | NR1H4PTAFRKDM4EHSD17B10HTT | |
| SCHEMBL28948669 | 0.85 | KDM4E (0.49) | PTAFRKDM4EHSD17B10HTTLMNA | |
| SCHEMBL28819624 | 0.84 | KDM4E (0.46) | PTAFRKDM4EHSD17B10HTTALDH1A1 | |
| SCHEMBL28819587 | 0.84 | KDM4E (0.48) | PTAFRKDM4EHSD17B10HTTALDH1A1 | |
| SCHEMBL28819741 | 0.83 | KDM4E (0.47) | PTAFRKDM4EHSD17B10HTTALDH1A1 | |
| SCHEMBL28819659 | 0.83 | PIN1 (0.52) | KDM4EHSD17B10HTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |