SCHEMBL28819794

SCHEMBL28819794

O=C(O)c1ccc(Cl)cc1S(=O)(=O)Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.57
TSHR P16473 2/20 0.57
CASP1 P29466 1/20 0.57
ALDH1A1 P00352 2/20 0.52
TP53 P04637 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
HSD17B10 Q99714 2/20 0.49
HPGD P15428 1/20 0.49
ACLY P53396 3/20 0.46
MYC P01106 2/20 0.45
TRPV4 Q9HBA0 1/20 0.44
F7 P08709 1/20 0.43
F3 P13726 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP1A2 P05177 1/20 0.43
KDM4E B2RXH2 2/20 0.42
GRIK1 P39086 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29236826 0.85 NR4A1 (0.53) SMN1; SMN2TSHRCASP1ALDH1A1TP53
SCHEMBL3907824 0.85 CASP1 (0.57) SMN1; SMN2TSHRCASP1ALDH1A1TP53
SCHEMBL3524715 0.85 ALDH1A1 (0.57) SMN1; SMN2TSHRCASP1ALDH1A1TP53
SCHEMBL10743411 0.83 CA1 (0.56) SMN1; SMN2TSHRCASP1ALDH1A1TP53
SCHEMBL2795074 0.83 TRPV4 (0.47) SMN1; SMN2TSHRCASP1ALDH1A1HSD17B10
SCHEMBL2126878 0.83 SMN1; SMN2 (0.55) SMN1; SMN2TSHRCASP1ALDH1A1TP53
SCHEMBL7922220 0.81 CDC25B (0.50) SMN1; SMN2TSHRTP53CA1CA2
SCHEMBL8488697 0.80 SMN1; SMN2 (0.52) SMN1; SMN2TSHRCASP1ALDH1A1TP53
SCHEMBL5930871 0.79 PTPRC (0.41) SMN1; SMN2TSHRCASP1ALDH1A1TP53
SCHEMBL10595756 0.79 TSHR (0.50) SMN1; SMN2TSHRCASP1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920670-B Preparation method of 5-chloro-2-aminobenzenesulfonamide 泽升科技(广州)有限公司 2022-10-21 CN claimed
CN-114920670-A Preparation method of 5-chloro-2-aminobenzenesulfonamide 泽升科技(广州)有限公司 2022-08-19 CN claimed
CN-114920670-B Preparation method of 5-chloro-2-aminobenzenesulfonamide 泽升科技(广州)有限公司 2022-10-21 CN disclosed
CN-114920670-B Preparation method of 5-chloro-2-aminobenzenesulfonamide 泽升科技(广州)有限公司 2022-10-21 CN disclosed
CN-114920670-A Preparation method of 5-chloro-2-aminobenzenesulfonamide 泽升科技(广州)有限公司 2022-08-19 CN disclosed
CN-114920670-A Preparation method of 5-chloro-2-aminobenzenesulfonamide 泽升科技(广州)有限公司 2022-08-19 CN disclosed