Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19437582 | 0.86 | ALDH1A1 (0.52) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E | |
| SCHEMBL2126878 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E | |
| SCHEMBL28819794 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E | |
| SCHEMBL3907824 | 0.80 | CASP1 (0.57) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E | |
| SCHEMBL8657781 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E | |
| SCHEMBL17494889 | 0.79 | GLA (0.44) | SMN1; SMN2TSHRALDH1A1KDM4EMYC | |
| SCHEMBL10743411 | 0.79 | CA1 (0.56) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E | |
| SCHEMBL6891924 | 0.77 | HPGD (0.64) | SMN1; SMN2TSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL13911395 | 0.76 | ALDH1A1 (0.50) | TSHRALDH1A1KDM4ETP53LMNA | |
| SCHEMBL11595770 | 0.76 | HSD17B10 (0.49) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| CN-1037437-C | New herbicides | RHONE POULENC AGRICULTURE | 1998-02-18 | — | — | CN | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| CN-1089258-A | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1994-07-13 | — | — | CN | disclosed |