SCHEMBL8101437

SCHEMBL8101437

CCOC(CC)(OCC)c1ccccc1C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ACHE P22303 1/20 0.35
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
NLRP3 Q96P20 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25838476 0.85 TSHR (0.32) TSHRACHENLRP3
SCHEMBL14163871 0.80 TSHR (0.35) TSHRACHEGABRA1GABRB2NLRP3
SCHEMBL9507129 0.78 GABRA1 (0.36) TSHRACHEGABRA1GABRB2NLRP3
SCHEMBL13450447 0.78 GABRA1 (0.36) TSHRACHEGABRA1GABRB2NLRP3
SCHEMBL28820101 0.76 TSHR (0.35) TSHRACHEGABRA1GABRB2NLRP3
SCHEMBL28092974 0.76 TSHR (0.35) TSHRACHEGABRA1GABRB2NLRP3
SCHEMBL12713575 0.72 ACHE (0.39) TSHRACHEGABRA1GABRB2
SCHEMBL11431192 0.72 ACHE (0.39) TSHRACHEGABRA1GABRB2
SCHEMBL5962153 0.72 KCNN4 (0.40)
SCHEMBL5588546 0.72 ALDH1A1 (0.38) TSHRACHEGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975570-A1 PHENOKETALS AND THE USE THEREOF AS ODORIFEROUS SUBSTANCES Cognis Deutschland GmbH (DE) 2000-02-02 EP disclosed
WO-1998045236-A1 PHENOKETALS AND THE USE THEREOF AS ODORIFEROUS SUBSTANCES COGNIS DEUTSCHLAND GMBH (DE) 1998-10-15 WO disclosed