Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101437 | 0.85 | TSHR (0.35) | TSHRACHENLRP3 | |
| SCHEMBL7606440 | 0.75 | KCNN4 (0.38) | TSHR | |
| SCHEMBL9507129 | 0.75 | GABRA1 (0.36) | TSHRACHEL3MBTL1ESR1NLRP3 | |
| SCHEMBL13450447 | 0.75 | GABRA1 (0.36) | TSHRACHEL3MBTL1ESR1NLRP3 | |
| SCHEMBL5590574 | 0.74 | ALDH1A1 (0.36) | TSHRACHEESR1ARESR2 | |
| SCHEMBL28820101 | 0.73 | TSHR (0.35) | TSHRACHENLRP3 | |
| SCHEMBL28092974 | 0.73 | TSHR (0.35) | TSHRACHENLRP3 | |
| SCHEMBL14163871 | 0.73 | TSHR (0.35) | TSHRACHENLRP3 | |
| SCHEMBL15656256 | 0.71 | ACHE (0.36) | TSHRACHEL3MBTL1ESR1AR | |
| SCHEMBL20210869 | 0.71 | CASR (0.39) | TSHRACHEL3MBTL1ESR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3722291-B1 | INDOLINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF FIBROTIC DISEASES | RESPIVERT LTD (GB) | 2023-07-19 | — | — | EP | disclosed |