SCHEMBL28822154

SCHEMBL28822154

COC1(OC)C(=Cc2ccccc2)c2ccccc2C1(C)C

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SERPINE1 P05121 1/20 0.33
MAOB P27338 2/20 0.32
HPGD P15428 3/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132951 0.70 ALDH1A1 (0.41) LMNAMAPK1SMN1; SMN2HSD17B10HPGD
SCHEMBL11871299 0.67 HPGD (0.44) LMNAMAPK1SMN1; SMN2HSD17B10MAOB
SCHEMBL11871293 0.67 HPGD (0.44) LMNAMAPK1SMN1; SMN2HSD17B10MAOB
SCHEMBL16746500 0.67 HPGD (0.44) LMNAMAPK1SMN1; SMN2HSD17B10MAOB
SCHEMBL29404946 0.64 CMA1 (0.35) LMNASMN1; SMN2MAOBHPGDMEN1
SCHEMBL132952 0.63 ALDH1A1 (0.41) LMNAMAPK1SMN1; SMN2HPGDMEN1
SCHEMBL30349347 0.63 ALDH1A1 (0.41) LMNAMAPK1SMN1; SMN2HPGDMEN1
SCHEMBL18383337 0.63 PDK2 (0.44) LMNASMN1; SMN2MEN1MAPTKMT2A
SCHEMBL29386757 0.63 PDK2 (0.44) LMNASMN1; SMN2MEN1MAPTKMT2A
SCHEMBL13508396 0.62 ALDH1A1 (0.42) LMNAMAPK1SMN1; SMN2HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4706780-A2 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS Symrise AG (DE) 2026-03-11 EP disclosed
CN-104837531-A Active substance combination for skin lightening I HENKEL AG & CO KGAA 2015-08-12 CN disclosed