SCHEMBL132952

SCHEMBL132952

COC1(OC)c2ccccc2C(=O)C1(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
MAPT P10636 5/20 0.38
KDM4E B2RXH2 3/20 0.38
CYP2D6 P10635 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
BLM P54132 2/20 0.38
CDC25A P30304 2/20 0.38
CDC25B P30305 2/20 0.38
MAP2K7 O14733 1/20 0.38
GMNN O75496 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30349347 1.00 ALDH1A1 (0.41) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL132951 0.85 ALDH1A1 (0.41) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL3369898 0.77 ALDH1A1 (0.48) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL6806744 0.74 PPIB (0.37) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL29173988 0.74 ALDH1A1 (0.45) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL29404946 0.73 CMA1 (0.35) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL2820392 0.72 ALDH1A1 (0.44) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL12261398 0.72 ALDH1A1 (0.46) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL10868939 0.69 MAPT (0.40) ALDH1A1MAPTKDM4ECYP2D6SMN1; SMN2
SCHEMBL11493691 0.68 MAPT (0.45) ALDH1A1MAPTKDM4ECYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190290560-A1 High SPF, Photo-protective Zinc Oxide Sunscreen Emulsions AMAVARA INC (US) 2019-09-26 US claimed
US-20190183754-A1 High SPF, Photoprotective Anhydrous Zinc Oxide Sunscreen Compositions AMAVARA INC (US) 2019-06-20 US claimed
EP-2931382-B1 ACTIVE SUBSTANCE COMBINATION FOR SKIN LIGHTENING I HENKEL AG & CO KGAA (DE) 2018-06-27 EP claimed
EP-2931382-A2 ACTIVE SUBSTANCE COMBINATION FOR SKIN LIGHTENING I Henkel AG&Co. KGAA (DE) 2015-10-21 EP claimed
WO-2014090526-A2 ACTIVE SUBSTANCE COMBINATION FOR SKIN LIGHTENING I HENKEL AG & CO. KGAA (DE) 2014-06-19 WO claimed
US-20260041094-A1 Compositions Comprising an Antimicrobial Boosting Agent SYMRISE AG (DE) 2026-02-12 US disclosed
US-20260021025-A1 STRUCTURALLY DIVERSE, STABLE, AND RADIATION-PROTECTIVE PARTICLE MATRIX SUNSCREEN AND COSMETIC COMPOSITIONS AND RELATED METHODS LCS ADVANCED SOLUTIONS LLC (US) 2026-01-22 US disclosed
WO-2025031562-A1 MYCOSPORINE-LIKE AMINO ACID ANALOGUE COMPOUNDS AND USE THEREOF SYMRISE AG (DE) 2025-02-13 WO disclosed
US-20250041179-A1 ANTIMICROBIAL COMBINATIONS SYMRISE AG (DE) 2025-02-06 US disclosed
US-12076436-B2 Bacterial ferment of Lactobacillus species SYMRISE AG (DE) 2024-09-03 US disclosed
US-12016944-B2 Mixtures comprising a protein extract for the treatment of human skin and/or hair SYMRISE AG (DE) 2024-06-25 US disclosed
US-20240130957-A1 EXTRACTS OF ISOCHRYSIS SPECIES/TISOCHRYSIS SPECIES SYMRISE AG (DE) 2024-04-25 US disclosed
EP-2455157-A1 Solubilizer for cosmetic preparations Symrise AG (DE) 2012-05-23 EP disclosed
US-20120058140-A1 TOPICAL COMPOSITIONS FOR INHIBITING MATRIX METALLOPROTEASES AND PROVIDING ANTIOXIDATIVE ACTIVITIES BATH & BODY WORKS BRAND MANAGEMENT, INC. (US) 2012-03-08 US disclosed
EP-2404595-A2 Method for manufacturing indanone derivatives Symrise AG (DE) 2012-01-11 EP disclosed
EP-2389922-A1 Cyclohexyl carbamate compounds as anti-ageing actives Symrise AG (DE) 2011-11-30 EP disclosed
EP-2356977-A1 Preparations with wood extracts of gleditsia Symrise AG (DE) 2011-08-17 EP disclosed
EP-2286908-A2 Solubilizer for cosmetic preparations Symrise AG (DE) 2011-02-23 EP disclosed
EP-2238967-A2 Skin treatment fighting skin aging II Henkel AG & Co. KGaA (DE) 2010-10-13 EP disclosed
EP-2238968-A2 Skin treatment fighting skin aging Henkel AG & Co. KGaA (DE) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190290560-A1 High SPF, Photo-protective Zinc Oxide Sunscreen Emulsions SLC30A7, SLC39A7, SOD1 ALDH1A1 1963/4885HSP90AA1 1011/4885HSP90AB1 848/4885
US-20120058140-A1 TOPICAL COMPOSITIONS FOR INHIBITING MATRIX METALLOPROTEASES AND PROVIDING ANTIOXIDATIVE ACTIVITIES TIMP3, MMP1, MMP9 ALDH1A1 2735/4885HSP90AA1 1327/4885HSP90AB1 1572/4885
US-20260041094-A1 Compositions Comprising an Antimicrobial Boosting Agent TLR7, MYC, ERG28 ALDH1A1 4611/4885HSP90AA1 1039/4885HSP90AB1 524/4885
US-20260021025-A1 STRUCTURALLY DIVERSE, STABLE, AND RADIATION-PROTECTIVE PARTICLE MATRIX SUNSCREEN AND COSMETIC COMPOSITIONS AND RELATED METHODS CYP24A1, TSLP, BRCA1 ALDH1A1 1269/4885HSP90AA1 362/4885HSP90AB1 307/4885
US-20250041179-A1 ANTIMICROBIAL COMBINATIONS C9, POLR1C, C1S ALDH1A1 1794/4885HSP90AA1 3327/4885HSP90AB1 2690/4885
US-20190183754-A1 High SPF, Photoprotective Anhydrous Zinc Oxide Sunscreen Compositions SP1, SOD3, SOD1 ALDH1A1 2496/4885HSP90AA1 1277/4885HSP90AB1 1016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.