SCHEMBL30349347

SCHEMBL30349347

COC1(OC)c2ccccc2C(=O)C1(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
MAPT P10636 5/20 0.38
KDM4E B2RXH2 3/20 0.38
CYP2D6 P10635 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
BLM P54132 2/20 0.38
CDC25A P30304 2/20 0.38
CDC25B P30305 2/20 0.38
MAP2K7 O14733 1/20 0.38
GMNN O75496 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132952 1.00 ALDH1A1 (0.41) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL132951 0.85 ALDH1A1 (0.41) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL3369898 0.77 ALDH1A1 (0.48) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL6806744 0.74 PPIB (0.37) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL29173988 0.74 ALDH1A1 (0.45) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL29404946 0.73 CMA1 (0.35) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL2820392 0.72 ALDH1A1 (0.44) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL12261398 0.72 ALDH1A1 (0.46) ALDH1A1HSP90AA1HSP90AB1MAPTKDM4E
SCHEMBL10868939 0.69 MAPT (0.40) ALDH1A1MAPTKDM4ECYP2D6SMN1; SMN2
SCHEMBL11493691 0.68 MAPT (0.45) ALDH1A1MAPTKDM4ECYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534685-B2 Fragrance composition SYMRISE AG (DE) 2026-01-27 US disclosed
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US disclosed
US-20250255833-A1 Compositions Comprising One or More (Bio)-Alkanediols with Antioxidants SYMRISE AG (DE) 2025-08-14 US disclosed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US disclosed
US-12303468-B2 Compositions comprising one or more (bio)-alkanediols with antioxidants SYMRISE AG (DE) 2025-05-20 US disclosed
US-12193441-B2 Antimicrobial mixtures comprising at least one hydroxyphenone derivative SYMRISE AG (DE) 2025-01-14 US disclosed
US-20240373845-A1 ANTIMICROBIAL MIXTURES COMPRISING AT LEAST ONE HYDROXYPHENONE DERIVATIVE SYMRISE AG (DE) 2024-11-14 US disclosed
US-11911347-B2 Compositions comprising one or more (bio)-alkanediols with antioxidants SYMRISE AG (DE) 2024-02-27 US disclosed
US-20230293408-A1 Compositions Comprising One or More (Bio)-Alkanediols with Antioxidants SYMRISE AG (DE) 2023-09-21 US disclosed
US-20230293403-A1 Compositions Comprising Lipophilic Compounds and One or More (Bio)-Alkanediols SYMRISE AG (DE) 2023-09-21 US disclosed
US-20230248663-A1 Compositions Comprising One or More (Bio)-Alkanediols with Antioxidants SYMRISE AG (US) 2023-08-10 US disclosed
US-20230159854-A1 A FRAGRANCE COMPOSITION SYMRISE AG (DE) 2023-05-25 US disclosed
US-20230131993-A1 COMPOSITION COMPRISING AN AVENANTHRAMIDE OR AN ANALOGUE THEREOF WITH IMPROVED STABILITY SYMRISE AG (DE) 2023-04-27 US disclosed
US-20230129036-A1 AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE SYMRISE AG (DE) 2023-04-27 US disclosed
US-20230118435-A1 COMPOSITION COMPRISING AN AVENANTHRAMIDE WITH IMPROVED SKIN PENETRATION SYMRISE AG (DE) 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293408-A1 Compositions Comprising One or More (Bio)-Alkanediols with Antioxidants MMP8, CXCL8, IL18 ALDH1A1 65/4885HSP90AA1 3015/4885HSP90AB1 2935/4885
US-20250255833-A1 Compositions Comprising One or More (Bio)-Alkanediols with Antioxidants MMP8, CXCL8, IL18 ALDH1A1 65/4885HSP90AA1 3015/4885HSP90AB1 2935/4885
US-20230293403-A1 Compositions Comprising Lipophilic Compounds and One or More (Bio)-Alkanediols CUTA, TRPA1, SMURF2 ALDH1A1 228/4885HSP90AA1 3324/4885HSP90AB1 3618/4885
US-12534685-B2 Fragrance composition NCLN, HCN2, TRPA1 ALDH1A1 1363/4885HSP90AA1 4588/4885HSP90AB1 4283/4885
US-20240373845-A1 ANTIMICROBIAL MIXTURES COMPRISING AT LEAST ONE HYDROXYPHENONE DERIVATIVE HPD, GRHPR, ALDH7A1 ALDH1A1 66/4885HSP90AA1 25/4885HSP90AB1 36/4885
US-12303468-B2 Compositions comprising one or more (bio)-alkanediols with antioxidants MMP8, CXCL8, IL18 ALDH1A1 65/4885HSP90AA1 3015/4885HSP90AB1 2935/4885
US-20230129036-A1 AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE HPD, CYP4A22, PAH ALDH1A1 551/4885HSP90AA1 631/4885HSP90AB1 632/4885
US-12193441-B2 Antimicrobial mixtures comprising at least one hydroxyphenone derivative HOGA1, GNPAT, CLPP ALDH1A1 43/4885HSP90AA1 9/4885HSP90AB1 14/4885
US-20230248663-A1 Compositions Comprising One or More (Bio)-Alkanediols with Antioxidants MMP8, CXCL8, IL18 ALDH1A1 65/4885HSP90AA1 3015/4885HSP90AB1 2935/4885
US-11911347-B2 Compositions comprising one or more (bio)-alkanediols with antioxidants MMP8, CXCL8, IL18 ALDH1A1 65/4885HSP90AA1 3015/4885HSP90AB1 2935/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 ALDH1A1 811/4885HSP90AA1 194/4885HSP90AB1 507/4885
US-20230131993-A1 COMPOSITION COMPRISING AN AVENANTHRAMIDE OR AN ANALOGUE THEREOF WITH IMPROVED STABILITY OAT, PIGS, HLA-A ALDH1A1 4343/4885HSP90AA1 3426/4885HSP90AB1 3092/4885
US-20230118435-A1 COMPOSITION COMPRISING AN AVENANTHRAMIDE WITH IMPROVED SKIN PENETRATION CUTA, ABCG2, MMP7 ALDH1A1 3976/4885HSP90AA1 2958/4885HSP90AB1 2585/4885
US-20230159854-A1 A FRAGRANCE COMPOSITION NISCH, NOS1, COXFA4 ALDH1A1 438/4885HSP90AA1 2176/4885HSP90AB1 2588/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 ALDH1A1 1377/4885HSP90AA1 1138/4885HSP90AB1 802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.