Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522876 | 0.88 | TSHR (0.46) | TSHRTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL6057969 | 0.85 | TSHR (0.43) | TSHRTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL10586114 | 0.83 | TDP1 (0.40) | TSHRTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL17186886 | 0.83 | ALDH1A1 (0.42) | TSHRTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL17242666 | 0.80 | TSHR (0.45) | TSHRTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL3393735 | 0.79 | GPR35 (0.46) | TSHRTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL2718367 | 0.79 | MAPT (0.44) | TSHRTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL17186888 | 0.79 | ALDH1A1 (0.41) | TSHRTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL2337048 | 0.79 | POLB (0.47) | TSHRTDP1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL16863642 | 0.78 | TSHR (0.40) | TSHRTDP1ALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226973-A2 | 4-Bis(2'-hydroxyethyl)amino-1-(3'-hydroxypropyl)amino-2-nitro-benzene, process for its preparation and means for dyeing hair | Wella Aktiengesellschaft (DE) | 1987-07-01 | — | — | EP | claimed |
| US-7211119-B2 | Coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-05-01 | — | — | US | disclosed |
| EP-1647266-A1 | New coupler components | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-04-19 | — | — | EP | disclosed |
| US-20060016024-A1 | Novel coupling components | PARALLEL WIRELESS, INC. | 2006-01-26 | — | — | US | disclosed |
| US-20060000032-A1 | Novel coupling components | HENKEL AG & CO. KGAA (DE) | 2006-01-05 | — | — | US | disclosed |
| EP-1585488-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-19 | — | — | EP | disclosed |
| EP-1583511-A1 | NOVEL COUPLING COMPONENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-12 | — | — | EP | disclosed |
| EP-1575910-A1 | DEVELOPING CONSTITUENTS FOR DYEING KERATIN FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2005072555-A2 | TREATMENT DEVICE FOR TREATING KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-08-11 | — | — | WO | disclosed |
| WO-2004058206-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004058205-A1 | NOVEL COUPLING COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004058690-A1 | DEVELOPING CONSTITUENTS FOR DYEING KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | disclosed |
| EP-1235673-A4 | METHOD OF FORMING A MEMBRANE, ESPECIALLY A LATEX OR POLYMER MEMBRANE, INCLUDING MULTIPLE DISCRETE LAYERS | BIO BARRIER INC (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030021903-A1 | Method of forming a membrane, especially a latex or polymer membrane, including multiple discrete layers | BECK, JOHN | 2003-01-30 | — | — | US | disclosed |
| EP-1235673-A2 | METHOD OF FORMING A MEMBRANE, ESPECIALLY A LATEX OR POLYMER MEMBRANE, INCLUDING MULTIPLE DISCRETE LAYERS | Bio Barrier, Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| US-20010018095-A1 | Method of forming a membrant, especially a latex or polymer membrane, including multiple discrete layers | SHLENKER ROBIN RENEE THILL (US) | 2001-08-30 | — | — | US | disclosed |
| US-5965276-A | A FIRST LAYER OF CURED LATEX, A SECOND LAYER COATING OF LATEX CONTAINING A BIOCIDE OR INDICATOR AND THE THIRD LAYER OF LATEX -THE SECOND LAYER PARTIALLY BONDED TO THE FIRST AND THIRD; PROTECTIVE CLOTHING; SURGICAL GLOVES; CODOOMS | BIO BARRIER, INC. (US) | 1999-10-12 | — | — | US | disclosed |
| WO-1999020203-A2 | METHOD OF FORMING A MEMBRANE, ESPECIALLY A LATEX OR POLYMER MEMBRANE, INCLUDING MULTIPLE DISCRETE LAYERS | BIO BARRIER, INC. (US) | 1999-04-29 | — | — | WO | disclosed |
| US-5549924-A | CONDOM, SURGERY GLOVES | Shlenker, Robin Renee Thill (US) | 1996-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060000032-A1 | Novel coupling components | KRT18, C9, H1-4 | TSHR 3210/4885TDP1 2982/4885ALDH1A1 450/4885 |
| US-20060016024-A1 | Novel coupling components | KRT18, H1-4, H1-3 | TSHR 3630/4885TDP1 2432/4885ALDH1A1 1969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.