Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20606051 | 0.84 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDGAACHEK1 | |
| SCHEMBL29856971 | 0.79 | CHEK1 (0.37) | KDM4EALDH1A1HPGDCHEK1CYP3A4 | |
| SCHEMBL26240985 | 0.76 | MAP2K2 (0.42) | KDM4EALDH1A1MAP2K2MAP2K1MKNK1 | |
| SCHEMBL12515332 | 0.74 | CYP3A4 (0.52) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL28285146 | 0.72 | CYP3A4 (0.61) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL30859597 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1GAAGLAHTT | |
| SCHEMBL6069006 | 0.69 | LCK (0.60) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL9793655 | 0.69 | KDM4E (0.53) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL33525781 | 0.69 | ADRA1A (0.50) | KDM4EALDH1A1GAACYP3A4TSHR | |
| SCHEMBL6181459 | 0.68 | KDM4E (0.51) | KDM4EALDH1A1HPGDPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195965-B | Inhibitors of WDR5 protein-protein binding | 普罗佩纶治疗公司 | 2022-07-26 | — | — | CN | disclosed |