SCHEMBL33525781

SCHEMBL33525781

COc1cc(=O)[nH]cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.50
GAA P10253 1/20 0.41
NPC1 O15118 1/20 0.41
HSP90AA1 P07900 3/20 0.41
MAPT P10636 3/20 0.41
MAPK1 P28482 3/20 0.41
RAB9A P51151 2/20 0.41
CACNA1B Q00975 2/20 0.41
APBA1 Q02410 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
APOBEC3G Q9HC16 2/20 0.41
ALDH1A1 P00352 1/20 0.41
PKM P14618 1/20 0.41
CCR6 P51684 1/20 0.41
TSHR P16473 1/20 0.38
HSP90AB1 P08238 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9670364 0.77 ALDH1A1 (0.49) MAPTRAB9AALDH1A1TSHRHTT
SCHEMBL9098928 0.77 ADRA1A (0.48) ADRA1AGAAHSP90AA1MAPTRAB9A
SCHEMBL16602449 0.74 ADRA1A (0.42) ADRA1AGAACYP2D6SLC6A4
SCHEMBL9669471 0.74 L3MBTL1 (0.54) GAANPC1MAPTRAB9AALDH1A1
SCHEMBL19789312 0.72 NQO2 (0.46) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11157567 0.72
SCHEMBL30507365 0.71
SCHEMBL15148389 0.71 GRIN2D (0.38) HSP90AA1MAPTMAPK1RAB9ACACNA1B
SCHEMBL16137887 0.71 GRIN2D (0.48) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL20606051 0.71 ALDH1A1 (0.49) GAAMAPTNPSR1ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 ADRA1A 149/4885GAA 2113/4885NPC1 802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.