Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | CDC42 | P60953 | 1/20 | 0.47 |
| ▸ | RAC1 | P63000 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882507 | 0.88 | L3MBTL1 (0.47) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 | |
| SCHEMBL2887225 | 0.86 | MEN1 (0.46) | MTNR1AMTNR1BAKR1C3AKR1C2TSHR | |
| SCHEMBL2884957 | 0.83 | MEN1 (0.46) | MTNR1AMTNR1BAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2887334 | 0.81 | KCNA5 (0.47) | MTNR1AMTNR1BCYP1A2TSHRL3MBTL1 | |
| SCHEMBL2882710 | 0.79 | MTNR1A (0.70) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 | |
| SCHEMBL2882707 | 0.79 | MTNR1A (0.70) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 | |
| SCHEMBL2882332 | 0.78 | MTNR1A (0.58) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 | |
| SCHEMBL2882337 | 0.78 | MTNR1A (0.58) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 | |
| SCHEMBL6791737 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1BCYP1A2L3MBTL1 | |
| SCHEMBL12383240 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1BAKR1C3AKR1C2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | MSD K.K. (JP) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | BMP6, GPR6, ACSL6 | MTNR1A 2869/4885MTNR1B 2349/4885AKR1C3 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.