Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCKAR | P32238 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882507 | 0.92 | L3MBTL1 (0.47) | L3MBTL1MTNR1AMTNR1BAOC3CHRM2 | |
| SCHEMBL2884957 | 0.86 | MEN1 (0.46) | MEN1KMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL2882340 | 0.86 | MTNR1A (0.58) | L3MBTL1MTNR1AMTNR1BTSHRAKR1C3 | |
| SCHEMBL2887334 | 0.81 | KCNA5 (0.47) | MEN1KMT2AL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL2887219 | 0.75 | MTNR1A (0.47) | MEN1KMT2AL3MBTL1CCKARMTNR1A | |
| SCHEMBL2887223 | 0.75 | MTNR1A (0.47) | MEN1KMT2AL3MBTL1CCKARMTNR1A | |
| SCHEMBL2807555 | 0.73 | L3MBTL1 (0.46) | L3MBTL1MTNR1AMTNR1BTSHRAKR1C3 | |
| SCHEMBL7688670 | 0.72 | L3MBTL1 (0.54) | L3MBTL1MTNR1AMTNR1BAOC3LMNA | |
| SCHEMBL2847001 | 0.71 | AKR1C3 (0.50) | L3MBTL1CCKARMTNR1AMTNR1BAOC3 | |
| SCHEMBL11390762 | 0.71 | AKR1C3 (0.69) | L3MBTL1MTNR1AMTNR1BAOC3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | MSD K.K. (JP) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | BMP6, GPR6, ACSL6 | MEN1 4377/4885KMT2A 3157/4885L3MBTL1 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.