Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17732726 | 0.91 | CA1 (0.55) | HTR2CCA1CA2CA9CA14 | |
| SCHEMBL17732708 | 0.91 | CA1 (0.55) | HTR2CCA1CA2CA9CA14 | |
| SCHEMBL17732716 | 0.91 | CA1 (0.55) | HTR2CCA1CA2CA9CA14 | |
| SCHEMBL28823734 | 0.85 | CA1 (0.50) | CA1CA2CA9CA14CA7 | |
| SCHEMBL28823799 | 0.82 | PPARD (0.41) | HTR2C | |
| SCHEMBL28823708 | 0.79 | CAMK2A (0.47) | HTR2CKMT2AMEN1SRD5A1HTR2A | |
| SCHEMBL28823682 | 0.79 | HTR2C (0.43) | HTR2CSRD5A1HTR2AHTR2BKDM1A | |
| SCHEMBL28823725 | 0.78 | LRRK2 (0.42) | KDM1ACYP19A1 | |
| SCHEMBL28967711 | 0.75 | PRCP (0.42) | — | |
| SCHEMBL19453963 | 0.75 | CA1 (0.60) | HTR2CCA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929691-A | Bicyclic compounds and uses thereof | 爱思开生物制药株式会社 | 2022-08-19 | — | — | CN | disclosed |