Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 6/20 | 0.36 |
| ▸ | PNMT | P11086 | 3/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708455 | 0.91 | KDM1A (0.43) | CAMK2APARP10PARP11KDM1APNMT | |
| SCHEMBL28823682 | 0.82 | HTR2C (0.43) | PARP10KDM1APNMTSRD5A1HTR2A | |
| SCHEMBL27760113 | 0.81 | PNMT (0.44) | CAMK2AKDM1APNMTASIC3ADRA2A | |
| SCHEMBL28823725 | 0.81 | LRRK2 (0.42) | KDM1APNMT | |
| SCHEMBL28823672 | 0.79 | HTR2C (0.49) | KDM1ASRD5A1HTR2AHTR2CHTR2B | |
| SCHEMBL27797441 | 0.78 | HTR2A (0.50) | PARP10PARP11KDM1APNMTASIC3 | |
| SCHEMBL28967711 | 0.78 | PRCP (0.42) | CAMK2AADRA2A | |
| SCHEMBL28823799 | 0.76 | PPARD (0.41) | HTR2C | |
| SCHEMBL28823734 | 0.76 | CA1 (0.50) | PARP1MEN1KMT2A | |
| SCHEMBL25296796 | 0.74 | CMA1 (0.33) | PARP10PARP11KDM1APNMTASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929691-A | Bicyclic compounds and uses thereof | 爱思开生物制药株式会社 | 2022-08-19 | — | — | CN | disclosed |