Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823672 | 0.85 | HTR2C (0.49) | CA1CA2CA7CA9CA14 | |
| SCHEMBL28823799 | 0.79 | PPARD (0.41) | PPARDPPARA | |
| SCHEMBL27913921 | 0.76 | CA1 (0.46) | CA1CA2CA7CA9CA14 | |
| SCHEMBL17732726 | 0.76 | CA1 (0.55) | CA1CA2CA7CA9CA14 | |
| SCHEMBL17732716 | 0.76 | CA1 (0.55) | CA1CA2CA7CA9CA14 | |
| SCHEMBL17732708 | 0.76 | CA1 (0.55) | CA1CA2CA7CA9CA14 | |
| SCHEMBL28823708 | 0.76 | CAMK2A (0.47) | PARP1KMT2AMEN1 | |
| SCHEMBL28823682 | 0.76 | HTR2C (0.43) | PARP1SLC6A2SLC6A4 | |
| SCHEMBL28043628 | 0.75 | CA1 (0.45) | CA1CA2CA7CA9CA14 | |
| SCHEMBL28823725 | 0.75 | LRRK2 (0.42) | PPARDCHRNB2CHRNA4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929691-A | Bicyclic compounds and uses thereof | 爱思开生物制药株式会社 | 2022-08-19 | — | — | CN | disclosed |