Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.42 |
| ▸ | PNMT | P11086 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823682 | 0.81 | HTR2C (0.43) | PNMTKDM1A | |
| SCHEMBL28823708 | 0.81 | CAMK2A (0.47) | PNMTKDM1A | |
| SCHEMBL28823672 | 0.78 | HTR2C (0.49) | KDM1ACYP19A1 | |
| SCHEMBL28967711 | 0.76 | PRCP (0.42) | — | |
| SCHEMBL2723160 | 0.76 | HTR6 (0.55) | LRRK2PNMTDRD2DRD3HTR6 | |
| SCHEMBL28823799 | 0.75 | PPARD (0.41) | PPARDPPARA | |
| SCHEMBL28823734 | 0.75 | CA1 (0.50) | CHRNB2CHRNA4PPARDPPARA | |
| SCHEMBL14893898 | 0.72 | HTR6 (0.45) | LRRK2PNMTDRD2DRD3HTR6 | |
| SCHEMBL17732769 | 0.71 | KDM1A (0.43) | DRD2DRD3KDM1A | |
| SCHEMBL28770047 | 0.71 | ADRA2A (0.41) | PNMTDRD2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929691-A | Bicyclic compounds and uses thereof | 爱思开生物制药株式会社 | 2022-08-19 | — | — | CN | disclosed |