Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824104 | 0.90 | MAPK10 (0.47) | MAPK9MAPK10FLT3SMN1; SMN2NPC1 | |
| SCHEMBL28949290 | 0.90 | DHODH (0.46) | SMN1; SMN2NPC1HSP90AA1NFKB1RAB9A | |
| SCHEMBL28824079 | 0.87 | NPC1 (0.40) | SMN1; SMN2NPC1HSP90AA1NFKB1RAB9A | |
| SCHEMBL28824058 | 0.85 | ALOX5AP (0.41) | MAPK9MAPK10SMN1; SMN2NPC1HSP90AA1 | |
| SCHEMBL28823984 | 0.85 | BRS3 (0.43) | SMN1; SMN2NPC1HSP90AA1NFKB1RAB9A | |
| SCHEMBL28824085 | 0.85 | TGFBR1 (0.46) | SMN1; SMN2NPC1HSP90AA1NFKB1RAB9A | |
| SCHEMBL28824031 | 0.85 | PLAUR (0.38) | MAPK9MAPK10SMN1; SMN2NPC1HSP90AA1 | |
| SCHEMBL28824037 | 0.84 | MCL1 (0.46) | SMN1; SMN2NPC1HSP90AA1NFKB1RAB9A | |
| SCHEMBL28824030 | 0.84 | DHODH (0.48) | SMN1; SMN2NPC1HSP90AA1NFKB1RAB9A | |
| SCHEMBL29851972 | 0.82 | TSHR (0.44) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |