Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2077909 | 0.87 | ALDH1A1 (0.51) | RPA1ALDH1A1GAAHTTHSD11B1 | |
| SCHEMBL14705877 | 0.86 | L3MBTL1 (0.48) | TSHRMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL16245907 | 0.86 | HSD11B1 (0.51) | TSHRMEN1KMT2ARPA1SMN1; SMN2 | |
| SCHEMBL31499492 | 0.84 | PIM2 (0.44) | TSHRCYP2D6MAPTCYP2C19HSD11B1 | |
| SCHEMBL28823984 | 0.83 | BRS3 (0.43) | KMT2ASMN1; SMN2GAA | |
| SCHEMBL28824102 | 0.82 | MAPK9 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28824030 | 0.82 | DHODH (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28824005 | 0.82 | ALDH1A1 (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28824037 | 0.82 | MCL1 (0.46) | TSHRMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28824043 | 0.82 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |