SCHEMBL28824554

SCHEMBL28824554

CCC(=O)C(OC)(OC)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27699208 0.76 DGAT1 (0.33)
SCHEMBL7732801 0.67
SCHEMBL13684732 0.67 TDP1 (0.33) ALOX15
SCHEMBL13545109 0.65 TDP1 (0.32) ALOX15
SCHEMBL27818206 0.65 ALOX15 (0.36) ALOX15
SCHEMBL20865671 0.65 ALOX15 (0.36) ALOX15
SCHEMBL10396197 0.65 TDP1 (0.33)
Propionamide SCHEMBL1685418 0.64
SCHEMBL17652003 0.63
SCHEMBL20641576 0.62 LMNA (0.35) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105263932-A Heterocyclic compound TAKEDA PHARMACEUTICAL 2016-01-20 CN disclosed