SCHEMBL27699208

SCHEMBL27699208

CCC(=O)C(OC)(OC)C(=O)OC

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.33
TSHR P16473 1/20 0.31
KCNN4 O15554 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9416764 0.79 DGAT1 (0.42) DGAT1TSHRKCNN4MEN1LMNA
SCHEMBL28824554 0.76 ALOX15 (0.33)
SCHEMBL4463173 0.73 DGAT1 (0.50) DGAT1TSHRKCNN4
SCHEMBL28668019 0.72 ALDH1A1 (0.40) DGAT1KCNN4MEN1LMNAMAPT
SCHEMBL4314333 0.71 ALDH1A1 (0.33) DGAT1TSHRKCNN4MEN1KMT2A
SCHEMBL31410419 0.71 ALDH1A1 (0.38) MEN1KMT2A
SCHEMBL9416745 0.70 DGAT1 (0.36) DGAT1KCNN4MEN1LMNAMAPT
SCHEMBL3169320 0.70 DGAT1 (0.37) DGAT1TSHR
SCHEMBL17611270 0.70 DGAT1 (0.37) DGAT1MEN1KMT2A
SCHEMBL28060314 0.70 DGAT1 (0.37) DGAT1TSHRKCNN4LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101163693-B Antibacterial piperidine derivatives ASTRAZENECA AB 2013-03-06 CN disclosed
CN-101163693-A Antibacterial piperidine derivatives ASTRAZENECA AB (SE) 2008-04-16 CN disclosed