Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 7/20 | 0.44 |
| ▸ | JAK2 | O60674 | 6/20 | 0.44 |
| ▸ | JAK1 | P23458 | 5/20 | 0.44 |
| ▸ | JAK3 | P52333 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898289 | 0.90 | LMNA (0.43) | SMN1; SMN2MAPK9MAPK10TYK2JAK2 | |
| SCHEMBL28824917 | 0.90 | LMNA (0.43) | SMN1; SMN2MAPK9MAPK10TYK2JAK2 | |
| SCHEMBL29898301 | 0.86 | LMNA (0.48) | SMN1; SMN2MAPK9TYK2JAK2CSF1R | |
| SCHEMBL28824948 | 0.86 | LMNA (0.48) | SMN1; SMN2MAPK9TYK2JAK2CSF1R | |
| SCHEMBL28824923 | 0.86 | HDAC3 (0.48) | SMN1; SMN2TYK2CSF1RSYKLMNA | |
| SCHEMBL28824929 | 0.84 | CSF1R (0.45) | SMN1; SMN2TYK2CSF1RAURKBSYK | |
| SCHEMBL29898255 | 0.80 | MAPT (0.45) | SMN1; SMN2CSF1RSYKLMNAMAPT | |
| SCHEMBL28824931 | 0.80 | MAPT (0.45) | SMN1; SMN2CSF1RSYKLMNAMAPT | |
| SCHEMBL28824932 | 0.80 | KDR (0.49) | SMN1; SMN2MAPK9MAPK10EGFRSYK | |
| SCHEMBL28824919 | 0.80 | BLK (0.49) | SMN1; SMN2TYK2AURKAAURKBSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989079-B | RIPK1 kinase target inhibitor and medical application thereof | 中国药科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-114989079-A | RIPK1 kinase target inhibitor and medical application thereof | 中国药科大学 | 2022-09-02 | — | — | CN | disclosed |