Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279054 | 0.74 | KDM4E (0.41) | ALDH1A1HTTLMNATSHRKDM4E | |
| SCHEMBL2895238 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HTTLMNAKMT2ATSHR | |
| SCHEMBL28046895 | 0.72 | PKM (0.50) | PKMALDH1A1HTTMCL1LMNA | |
| SCHEMBL9348700 | 0.70 | PKM (0.65) | PKMALDH1A1HTTMCL1LMNA | |
| SCHEMBL4483317 | 0.69 | ALDH1A1 (0.42) | ALDH1A1LMNAKMT2ATSHRKDM4E | |
| SCHEMBL4486268 | 0.69 | ACHE (0.42) | ALDH1A1LMNAKMT2ATSHRKDM4E | |
| SCHEMBL2905398 | 0.69 | PKM (0.59) | PKMALDH1A1HTTMCL1LMNA | |
| SCHEMBL2893131 | 0.69 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2ATSHRKDM4E | |
| SCHEMBL2889816 | 0.68 | KDM4E (0.52) | ALDH1A1LMNAKMT2ATSHRKDM4E | |
| SCHEMBL4351022 | 0.68 | MEN1 (0.47) | ALDH1A1LMNAKMT2ATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330651-A | 1,2,4-Triazolethione derivative containing (hetero)aryl group and piperazine, and preparation method and application thereof | UNIV NANKAI | 2016-02-17 | — | — | CN | disclosed |