Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825359 | 1.00 | PKM (0.38) | PKMPTPN1ALDH1A1GLATP53 | |
| SCHEMBL28047838 | 0.83 | PKM (0.43) | PKMPTPN1ALDH1A1GLATP53 | |
| SCHEMBL28825353 | 0.83 | PKM (0.43) | PKMPTPN1ALDH1A1GLATP53 | |
| SCHEMBL28047851 | 0.81 | ALDH1A1 (0.39) | PTPN1ALDH1A1GLATP53TSHR | |
| Hydrochloric Acid SCHEMBL28047835 | 0.71 | CYP2D6 (0.46) | MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28047741 | 0.71 | CYP2D6 (0.46) | MAPTMEN1KMT2A | |
| SCHEMBL28047757 | 0.70 | ALDH1A1 (0.45) | PKMPTPN1ALDH1A1GLATP53 | |
| SCHEMBL10887701 | 0.70 | ALDH1A1 (0.45) | PKMPTPN1ALDH1A1GLATP53 | |
| SCHEMBL28825355 | 0.69 | LMNA (0.40) | PKMLMNA | |
| SCHEMBL28047791 | 0.69 | LMNA (0.40) | PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |