Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | SI | P14410 | 6/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711540 | 0.78 | ALDH1A1 (0.44) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL713686 | 0.70 | PTPN11 (0.42) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL45441 | 0.70 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL714489 | 0.69 | RAB9A (0.53) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL714040 | 0.68 | ESR1 (0.40) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL6324818 | 0.68 | GAA (0.58) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| Hydrochloric Acid SCHEMBL3691525 | 0.68 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL6326577 | 0.68 | ALDH1A1 (0.59) | KDM4EALDH1A1HSD17B10HPGDMGAM | |
| SCHEMBL1002366 | 0.68 | FBP1 (0.30) | — | |
| SCHEMBL27856171 | 0.67 | GSK3B (0.43) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189506-A | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG | 2015-12-23 | — | — | CN | disclosed |