Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 20/20 | 0.43 |
| ▸ | RXRA | P19793 | 17/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825610 | 0.84 | GRIN1 (0.45) | GRIN1GRIN2BRXRA | |
| SCHEMBL28825578 | 0.77 | GRIN1 (0.41) | GRIN1GRIN2BRXRA | |
| SCHEMBL28825666 | 0.75 | GRIN1 (0.41) | GRIN1GRIN2BRXRA | |
| SCHEMBL28825471 | 0.73 | GRIN1 (0.38) | GRIN1GRIN2B | |
| SCHEMBL28825503 | 0.72 | MEN1 (0.41) | GRIN1GRIN2BRXRA | |
| SCHEMBL28825599 | 0.71 | GRIN1 (0.46) | GRIN1GRIN2BRXRA | |
| SCHEMBL28825609 | 0.71 | GRIN1 (0.42) | GRIN1GRIN2BRXRA | |
| SCHEMBL28825500 | 0.71 | RAB9A (0.40) | GRIN1GRIN2B | |
| SCHEMBL28825536 | 0.68 | GRIN2B (0.37) | GRIN1GRIN2BRXRA | |
| SCHEMBL18143912 | 0.65 | NFE2L2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |