Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenanthroline SCHEMBL28825890 | 0.88 | MAP4K4 (0.54) | LMNAL3MBTL1GAAKDRMAP4K4 | |
| SCHEMBL28572462 | 0.80 | LMNA (0.77) | LMNAL3MBTL1MEN1KMT2APARP1 | |
| SCHEMBL28913640 | 0.79 | LMNA (0.74) | LMNAL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL28527433 | 0.77 | LMNA (0.89) | LMNAL3MBTL1GAAMEN1KMT2A | |
| 8-Aminoquinoline SCHEMBL28695606 | 0.77 | L3MBTL1 (0.56) | LMNAL3MBTL1GAAKDRMAP4K4 | |
| SCHEMBL7722989 | 0.77 | LMNA (0.96) | LMNAL3MBTL1MEN1KMT2ACYP3A4 | |
| SCHEMBL1052095 | 0.77 | LMNA (0.96) | LMNAL3MBTL1MEN1KMT2ACYP3A4 | |
| Iodoacetamide SCHEMBL5026078 | 0.75 | LMNA (0.68) | LMNAMEN1KMT2APARP1EGLN1 | |
| Glycine SCHEMBL28823989 | 0.75 | LMNA (0.68) | LMNAMEN1KMT2APARP1EGLN1 | |
| Phosphine SCHEMBL28009623 | 0.75 | LMNA (0.92) | LMNAL3MBTL1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105399740-A | Acridine derivative, preparation method thereof and application of same serving as anti-tumor drug | UNIV GUANGXI CHINESE MEDICINE | 2016-03-16 | — | — | CN | disclosed |