Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL28825892 | 0.88 | LMNA (0.56) | MAP4K4GAAL3MBTL1KDRPARP1 | |
| 8-Aminoquinoline SCHEMBL28695606 | 0.84 | L3MBTL1 (0.56) | MAP4K4GAAL3MBTL1KDRPARP1 | |
| SCHEMBL6070469 | 0.76 | MKNK2 (0.65) | MAP4K4PARP1SLC40A1LMNASMN1; SMN2 | |
| SCHEMBL9755467 | 0.74 | L3MBTL1 (0.69) | GAAL3MBTL1KDRSMN1; SMN2TP53 | |
| SCHEMBL21358860 | 0.74 | PSMD14 (0.61) | MAP4K4PARP1SLC40A1LMNASMN1; SMN2 | |
| SCHEMBL77931 | 0.73 | MAP4K4 (0.62) | MAP4K4L3MBTL1PARP1LMNASMN1; SMN2 | |
| SCHEMBL29959902 | 0.73 | MAP4K4 (0.62) | MAP4K4L3MBTL1PARP1LMNASMN1; SMN2 | |
| SCHEMBL12548430 | 0.71 | PIM1 (0.62) | L3MBTL1PARP1SLC40A1LMNASMN1; SMN2 | |
| Phenanthroline SCHEMBL9806287 | 0.71 | CCR1 (0.84) | L3MBTL1PARP1LMNASMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3772040 | 0.71 | MAP4K4 (0.60) | MAP4K4L3MBTL1PARP1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105399740-A | Acridine derivative, preparation method thereof and application of same serving as anti-tumor drug | UNIV GUANGXI CHINESE MEDICINE | 2016-03-16 | — | — | CN | disclosed |