SCHEMBL7722989

SCHEMBL7722989

[Cu].c1cnc2c(c1)ccc1ncccc12.c1cnc2c(c1)ccc1ncccc12

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.96
CYP3A4 P08684 2/20 0.64
CCR1 P32246 5/20 0.60
CCR8 P51685 5/20 0.60
MAPT P10636 3/20 0.60
HSP90AA1 P07900 3/20 0.60
CCR5 P51681 3/20 0.60
KDM4E B2RXH2 2/20 0.60
HTT P42858 2/20 0.60
HIF1A Q16665 2/20 0.60
MMP2 P08253 2/20 0.60
TSHR P16473 2/20 0.60
GMNN O75496 1/20 0.60
TP53 P04637 1/20 0.60
CYP2D6 P10635 1/20 0.60
MMP9 P14780 1/20 0.60
ALOX15 P16050 1/20 0.60
NFKB1 P19838 1/20 0.60
MMP8 P22894 1/20 0.60
THPO P40225 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1052095 1.00 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
Phosphine SCHEMBL28009623 0.98 LMNA (0.92) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL8313 0.98 LMNA (1.00) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL6513577 0.98 LMNA (1.00) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL723791 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL7142651 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL7268962 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL15788918 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
Iodide SCHEMBL10638043 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT
SCHEMBL3885158 0.96 LMNA (0.96) LMNACYP3A4CCR1CCR8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59099255-A None JP disclosed
US-20260001896-A1 LUMINESCENT SILAFLUORENE AND GERMAFLUORENE COMPOUNDS UNIV MISSOURI (US) 2026-01-01 US disclosed
US-12473308-B2 Luminescent silafluorene and germafluorene compounds THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2025-11-18 US disclosed
US-20220162235-A1 LUMINESCENT SILAFLUORENE AND GERMAFLUORENE COMPOUNDS NATIONAL SCIENCE FOUNDATION 2022-05-26 US disclosed
WO-2020210416-A1 LUMINESCENT SILAFLUORENE AND GERMAFLUORENE COMPOUNDS THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2020-10-15 WO disclosed
US-6391648-B1 ASSOCIATIONS FOR USE AS OPTICAL OXYGEN DETECTORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-05-21 US disclosed
US-5031449-A Copper or oxide particles in ionomer SHIMADZU CORPORATION (JP) 1991-07-16 US disclosed
JP-S5999255-A HIGH-SENSITIVE ANALYSIS OF SACCHARIDE TOYO SODA MFG CO LTD 1984-06-07 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220162235-A1 LUMINESCENT SILAFLUORENE AND GERMAFLUORENE COMPOUNDS SLCO2A1, GLO1, GLMN LMNA 900/4885CYP3A4 750/4885CCR1 1389/4885
US-12473308-B2 Luminescent silafluorene and germafluorene compounds SLCO2A1, GLO1, GLMN LMNA 900/4885CYP3A4 750/4885CCR1 1389/4885
US-20260001896-A1 LUMINESCENT SILAFLUORENE AND GERMAFLUORENE COMPOUNDS TAS2R13, TAS2R8, TAS2R10 LMNA 1603/4885CYP3A4 156/4885CCR1 543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.