Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.62 |
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.56 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | LIPE | Q05469 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589716 | 0.84 | BCL2 (0.56) | RAB9ANPC1SMN1; SMN2MAPK1NAMPT | |
| SCHEMBL29591000 | 0.83 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL28052479 | 0.83 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL15355311 | 0.82 | SMN1; SMN2 (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29589853 | 0.82 | SMN1; SMN2 (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28826015 | 0.80 | LIPE (0.62) | SMN1; SMN2TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL29560919 | 0.80 | L3MBTL1 (0.66) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28052547 | 0.80 | LIPE (0.56) | RAB9ANPC1SMN1; SMN2HPGDNOTUM | |
| SCHEMBL28052500 | 0.80 | L3MBTL1 (0.66) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28052545 | 0.80 | MAPT (0.66) | RAB9ANPC1SMN1; SMN2HPGDNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431422-A | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2016-03-23 | — | — | CN | disclosed |