Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27933392 | 0.87 | NOTUM (0.66) | NOTUMTP53MAPTTSHRALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL29082677 | 0.86 | NOTUM (0.47) | NOTUMTP53MAPTTSHRALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27868448 | 0.86 | NOTUM (0.62) | NOTUMPTGS2TP53MAPTTSHR | |
| Ethoxycarbonyl Group SCHEMBL28826450 | 0.83 | NOTUM (0.47) | NOTUMTP53MAPTTSHRALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL29082690 | 0.82 | NOTUM (0.48) | NOTUMTP53ALDH1A1TLR8KDM4E | |
| Ethoxycarbonyl Group SCHEMBL27851503 | 0.81 | TSHR (0.44) | NOTUMTP53MAPTTSHRALDH1A1 | |
| SCHEMBL9096052 | 0.80 | NOTUM (0.64) | NOTUMMAPTCYP3A4CYP2D6PSEN1 | |
| Ethoxycarbonyl Group SCHEMBL29082342 | 0.78 | KMT2A (0.36) | PTGS2MAPTTSHRALDH1A1LMNA | |
| Ethoxycarbonyl Group SCHEMBL27921877 | 0.77 | PTGS2 (0.50) | NOTUMPTGS2TP53CYP3A4ALDH1A1 | |
| 1,4-Dichlorobenzene SCHEMBL27842897 | 0.76 | HSD17B10 (0.42) | PTGS2MAPTTSHRCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103209979-B | therapeutic agent 976 | ASTRAZENECA AB (SE) | 2016-02-10 | — | — | CN | disclosed |