Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30578696 | 0.83 | NOTUM (0.65) | NOTUMRAB9AHPGDALDH1A1MAPK1 | |
| Ethoxycarbonyl Group SCHEMBL28826453 | 0.82 | NOTUM (0.48) | NOTUMRAB9AHPGDALDH1A1MAPK1 | |
| Ethoxycarbonyl Group SCHEMBL29082677 | 0.80 | NOTUM (0.47) | NOTUMRAB9AHPGDALDH1A1MAPK1 | |
| Ethoxycarbonyl Group SCHEMBL27933392 | 0.78 | NOTUM (0.66) | NOTUMRAB9AHPGDALDH1A1MAPK1 | |
| Ethoxycarbonyl Group SCHEMBL27868448 | 0.77 | NOTUM (0.62) | NOTUMRAB9AHPGDALDH1A1NPC1 | |
| Ethoxycarbonyl Group SCHEMBL28826450 | 0.77 | NOTUM (0.47) | NOTUMRAB9AHPGDALDH1A1NPC1 | |
| Ethoxycarbonyl Group SCHEMBL27851503 | 0.75 | TSHR (0.44) | NOTUMRAB9AALDH1A1NPC1TP53 | |
| Ethoxycarbonyl Group SCHEMBL27852394 | 0.73 | HTR2A (0.40) | RAB9AHPGDALDH1A1PPARG | |
| SCHEMBL29082692 | 0.72 | NOTUM (0.46) | NOTUMRAB9AALDH1A1NPC1LMNA | |
| Ethoxycarbonyl Group SCHEMBL27921877 | 0.72 | PTGS2 (0.50) | NOTUMRAB9AHPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768877-A | ISR inhibitor and preparation method and application thereof | 中国药科大学 | 2023-09-19 | — | — | CN | disclosed |