Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16336632 | 0.76 | SLC22A12 (0.38) | HSD11B1ALDH1A1GAASMN1; SMN2HTR6 | |
| SCHEMBL16382718 | 0.74 | SLC22A12 (0.40) | HSD11B1ALDH1A1GAASMN1; SMN2HTR6 | |
| SCHEMBL31487098 | 0.71 | GAA (0.47) | HSD11B1ALDH1A1GAASMN1; SMN2HTR6 | |
| SCHEMBL15598377 | 0.71 | CA1 (0.46) | HSD11B1ALDH1A1GAAHTR6CA1 | |
| SCHEMBL20504677 | 0.70 | AGTR1 (0.48) | ALDH1A1GAASMN1; SMN2HTR6AGTR1 | |
| SCHEMBL16382704 | 0.70 | ALDH1A1 (0.36) | HSD11B1ALDH1A1GAASMN1; SMN2HTR6 | |
| SCHEMBL15564770 | 0.69 | L3MBTL1 (0.52) | HSD11B1ALDH1A1HTR6CA1CA2 | |
| SCHEMBL16916209 | 0.69 | CNR2 (0.38) | GAAHTR6CA1CA2PTGDR2 | |
| SCHEMBL16337138 | 0.68 | RAPGEF4 (0.39) | HSD11B1ALDH1A1HTR6CA1CA2 | |
| SCHEMBL28259252 | 0.68 | GAA (0.46) | ALDH1A1GAASMN1; SMN2HTR6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105530932-A | Primary carboxamides as BIK inhibitors | ABBVIE INC | 2016-04-27 | — | — | CN | disclosed |