Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.63 |
| ▸ | METAP2 | P50579 | 9/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28058501 | 0.86 | METAP2 (0.68) | IDO1METAP2SIRT3METAP1KEAP1 | |
| SCHEMBL5025520 | 0.79 | IDO1 (1.00) | IDO1METAP2SIRT3BRAFMETAP1 | |
| Ethoxycarbonyl Group SCHEMBL28058388 | 0.78 | METAP2 (0.65) | IDO1METAP2SIRT3METAP1KEAP1 | |
| Pyrazine SCHEMBL27608305 | 0.70 | KMT2A (0.31) | — | |
| Ethoxycarbonyl Group SCHEMBL27777585 | 0.70 | LMNA (0.37) | — | |
| Ethoxycarbonyl Group SCHEMBL27620342 | 0.70 | GCGR (0.36) | — | |
| SCHEMBL22627332 | 0.69 | METAP2 (0.62) | IDO1METAP2METAP1KEAP1NOTUM | |
| Methyl 4-Pyridylketone SCHEMBL28024697 | 0.69 | KMT2A (0.46) | — | |
| Ethoxycarbonyl Group SCHEMBL27750267 | 0.68 | KMT2A (0.53) | — | |
| Ethoxycarbonyl Group SCHEMBL27620341 | 0.68 | GCGR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541796-A | Synthetic method of NH-1,2,3-triazole bipyridine compounds | WUHAN INST TECHNOLOGY | 2016-05-04 | — | — | CN | disclosed |