Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27978135 | 0.77 | NOS3 (0.36) | — | |
| SCHEMBL25714211 | 0.61 | NOS3 (0.36) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL18425409 | 0.60 | — | — | |
| SCHEMBL6487464 | 0.59 | — | — | |
| SCHEMBL17673728 | 0.59 | NOS3 (0.30) | — | |
| SCHEMBL27978259 | 0.59 | KDR (0.36) | LMNA | |
| SCHEMBL28416922 | 0.58 | — | — | |
| SCHEMBL12238834 | 0.58 | ADORA3 (0.30) | — | |
| SCHEMBL28166978 | 0.56 | ADORA3 (0.31) | — | |
| SCHEMBL4646183 | 0.54 | NOS2 (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104024226-B | Novel nicotinamide derivative or salt thereof | FUJIFILM CORP. (JP) | 2016-06-01 | — | — | CN | disclosed |