Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28766354 | 0.89 | GABRA1 (0.35) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28461904 | 0.79 | TPMT (0.46) | CA1CA2PTPN1 | |
| SCHEMBL26354787 | 0.79 | NOS3 (0.44) | NPC1RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL28459756 | 0.79 | CES2 (0.48) | CES2CES1CA1CA2RAB9A | |
| SCHEMBL16161613 | 0.79 | ALDH1A1 (0.48) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28456387 | 0.79 | CES2 (0.48) | CES2CES1CA1CA2NPC1 | |
| SCHEMBL16612045 | 0.79 | PARP10 (0.43) | CA1CA2KMT2AMAPT | |
| SCHEMBL28472299 | 0.79 | CES2 (0.53) | CES2CES1PTPN1MEN1KMT2A | |
| SCHEMBL17218754 | 0.79 | CES2 (0.53) | CES2CES1NPC1RAB9AMEN1 | |
| SCHEMBL13449660 | 0.78 | CES1 (0.44) | CES2CES1CA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957113-B | 2-chloroquinoline-3-formaldehyde oxime-O- (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2023-05-09 | — | — | CN | claimed |
| CN-114957112-B | (2-chloroquinoline-3-yl) methyl (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2023-01-17 | — | — | CN | claimed |
| CN-114957112-A | (2-chloroquinoline-3-yl) methyl (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2022-08-30 | — | — | CN | claimed |
| CN-114957113-A | 2-chloroquinoline-3-formaldehyde oxime-O- (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2022-08-30 | — | — | CN | claimed |
| CN-114957113-B | 2-chloroquinoline-3-formaldehyde oxime-O- (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-114957113-B | 2-chloroquinoline-3-formaldehyde oxime-O- (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-114957112-B | (2-chloroquinoline-3-yl) methyl (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-114957112-B | (2-chloroquinoline-3-yl) methyl (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-111662202-B | Synthetic method of alpha-ketoamide compound | 五邑大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-114957113-A | 2-chloroquinoline-3-formaldehyde oxime-O- (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114957112-A | (2-chloroquinoline-3-yl) methyl (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114957113-A | 2-chloroquinoline-3-formaldehyde oxime-O- (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114957112-A | (2-chloroquinoline-3-yl) methyl (N-p-fluorophenyl) carbamate and preparation method and application thereof | 渤海大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111875544-B | Synthesis method of N-substituted hydantoin compound | 五邑大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-111875544-A | Synthesis method of N-substituted hydantoin compound | 五邑大学 | 2020-11-03 | — | — | CN | disclosed |
| CN-111662202-A | Synthetic method of alpha-ketoamide compound | 五邑大学 | 2020-09-15 | — | — | CN | disclosed |