Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | CPS1 | P31327 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828587 | 0.90 | CYP1A1 (0.42) | CTSACYP2C19ERN1 | |
| SCHEMBL28828711 | 0.87 | TDP2 (0.43) | CTSA | |
| SCHEMBL28828754 | 0.87 | AKR1C3 (0.38) | AKR1C3AKR1C2KLKB1CTSAFFAR1 | |
| SCHEMBL29121265 | 0.87 | AKR1C3 (0.38) | AKR1C3AKR1C2KLKB1CTSAFFAR1 | |
| SCHEMBL28828756 | 0.87 | CHRNB2 (0.39) | — | |
| SCHEMBL28828554 | 0.85 | F2 (0.41) | FFAR1KDM1A | |
| SCHEMBL28828407 | 0.83 | RXRA (0.36) | FFAR1CYP2C19 | |
| SCHEMBL29121229 | 0.83 | GRM2 (0.41) | AKR1C3AKR1C2KLKB1CTSAFFAR1 | |
| SCHEMBL29228297 | 0.83 | GRM2 (0.41) | AKR1C3AKR1C2KLKB1CTSAFFAR1 | |
| SCHEMBL28828450 | 0.81 | KDM1A (0.36) | KLKB1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |