Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775875 | 0.75 | ACHE (0.43) | ACHEGAANFE2L2 | |
| SCHEMBL514390 | 0.73 | ACHE (0.42) | ACHEGAANFE2L2 | |
| SCHEMBL31005130 | 0.72 | ACHE (0.50) | ACHEGAANFE2L2 | |
| SCHEMBL3207396 | 0.72 | ACHE (0.50) | ACHEGAANFE2L2 | |
| SCHEMBL2460604 | 0.71 | ACHE (0.40) | ACHEGAANFE2L2 | |
| SCHEMBL18195202 | 0.71 | ACHE (0.40) | ACHEGAANFE2L2 | |
| SCHEMBL31339586 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL29143241 | 0.69 | TSHR (0.38) | GAA | |
| SCHEMBL776881 | 0.69 | — | — | |
| SCHEMBL777872 | 0.68 | ACHE (0.37) | ACHENFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372550-A | Aryl ether and application thereof | 佩洛通治疗公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105530923-B | Aryl ethers and their use | 佩洛通治疗公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-105530923-A | Aryl ethers and their use | PELOTON THERAPEUTICS INC | 2016-04-27 | — | — | CN | disclosed |