Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28830428 | 0.91 | ALDH1A1 (0.33) | ALDH1A1MAPTHSD11B1L3MBTL1KMT2A | |
| SCHEMBL28830521 | 0.91 | ALDH1A1 (0.33) | ALDH1A1MAPTHSD11B1L3MBTL1KMT2A | |
| SCHEMBL28830435 | 0.91 | ALDH1A1 (0.33) | ALDH1A1MAPTHSD11B1L3MBTL1KMT2A | |
| SCHEMBL28950453 | 0.86 | ALDH1A1 (0.34) | ALDH1A1MAPTHSD11B1L3MBTL1LMNA | |
| SCHEMBL28830403 | 0.85 | NAMPT (0.39) | ALDH1A1MAPTMETKMT2ALMNA | |
| SCHEMBL28830400 | 0.85 | NAMPT (0.39) | ALDH1A1MAPTMETKMT2ALMNA | |
| SCHEMBL28830482 | 0.84 | L3MBTL1 (0.35) | ALDH1A1MAPTHSD11B1METL3MBTL1 | |
| SCHEMBL23120044 | 0.82 | L3MBTL1 (0.37) | ALDH1A1MAPTHSD11B1L3MBTL1KMT2A | |
| SCHEMBL29634559 | 0.82 | LMNA (0.35) | ALDH1A1MAPTHSD11B1L3MBTL1KMT2A | |
| SCHEMBL29751749 | 0.81 | GPR174 (0.35) | ALDH1A1MAPTHSD11B1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724142-B | Amide or sulfonamide substituted hydrazine derivatives as JAK kinase inhibitors | 启元生物(杭州)有限公司 | 2022-09-02 | — | — | CN | disclosed |