Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761736 | 0.90 | GPR119 (0.58) | GPR119CYP2C9 | |
| SCHEMBL288620 | 0.88 | GPR119 (0.56) | GPR119CYP2C9 | |
| SCHEMBL757761 | 0.87 | GPR119 (0.69) | GPR119CYP2C9 | |
| SCHEMBL10170858 | 0.86 | GPR119 (0.46) | GPR119CYP2C9 | |
| SCHEMBL4479275 | 0.82 | GPR119 (0.76) | GPR119CYP2C9 | |
| SCHEMBL3716443 | 0.79 | GPR119 (0.47) | GPR119CYP2C9 | |
| SCHEMBL4493103 | 0.77 | GPR119 (0.77) | GPR119CYP2C9 | |
| SCHEMBL4495979 | 0.76 | GPR119 (1.00) | GPR119CYP2C9 | |
| SCHEMBL288618 | 0.76 | GPR119 (0.75) | GPR119CYP2C9 | |
| SCHEMBL288249 | 0.76 | GPR119 (0.57) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427450-A1 | GPR 119 MODULATORS | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20120052130-A1 | GPR 119 MODULATORS | PFIZER INC. | 2012-03-01 | — | — | US | disclosed |
| WO-2010128425-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100285145-A1 | GPR 119 MODULATORS | PFIZER INC | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052130-A1 | GPR 119 MODULATORS | GPR119, GPR39, GPR65 | GPR119 1/4885CYP2C9 722/4885 |
| US-20100285145-A1 | GPR 119 MODULATORS | GPR119, GPR65, GPR39 | GPR119 1/4885CYP2C9 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.