Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | RXRB | P28702 | 2/20 | 0.54 |
| ▸ | BCL2 | P10415 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
| ▸ | FNTA | P49354 | 2/20 | 0.51 |
| ▸ | FNTB | P49356 | 2/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655399 | 0.89 | FOLH1 (0.66) | NR4A2FOLH1MRGPRX4 | |
| SCHEMBL30578357 | 0.89 | FOLH1 (0.66) | NR4A2FOLH1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL27689479 | 0.87 | FOLH1 (0.63) | NR4A2FOLH1MRGPRX4 | |
| SCHEMBL5519447 | 0.84 | KMO (0.63) | KMONR4A2RXRARXRBBCL2 | |
| SCHEMBL30725957 | 0.82 | KMO (0.86) | KMORXRARXRB | |
| SCHEMBL29904709 | 0.82 | KMO (0.86) | KMORXRARXRB | |
| SCHEMBL71238 | 0.82 | KMO (0.86) | KMORXRARXRB | |
| SCHEMBL1252499 | 0.82 | CFD (0.66) | KMONR4A2RXRARXRBBCL2 | |
| SCHEMBL12894987 | 0.82 | BCL2 (0.78) | KMONR4A2RXRARXRBBCL2 | |
| Hydrochloric Acid SCHEMBL4350309 | 0.80 | KMO (0.83) | KMORXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814038-B | Benzimidazole derivatives as EP4 ligands | 拜耳医药股份公司 | 2018-12-04 | — | — | CN | disclosed |
| CN-105814038-A | Benzimidazole derivatives as EP4 ligands | 拜耳医药股份公司 | 2016-07-27 | — | — | CN | disclosed |