Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278890 | 0.84 | ALDH1A1 (0.40) | FOLH1NR1H4ANPEPENPEPALDH1A1 | |
| SCHEMBL6094753 | 0.77 | FOLH1 (0.42) | FOLH1ALDH1A1 | |
| SCHEMBL15955226 | 0.75 | ANPEP (0.41) | NR1H4ANPEPENPEPMEP1BALDH1A1 | |
| SCHEMBL15537367 | 0.74 | EPHX1 (0.49) | FOLH1ANPEPENPEPMEP1B | |
| SCHEMBL557761 | 0.71 | MEP1B (0.51) | FOLH1NR1H4SLC7A5MEP1B | |
| SCHEMBL3629077 | 0.71 | SLC7A5 (0.52) | FOLH1SLC7A5ANPEPENPEPMEP1B | |
| SCHEMBL3992230 | 0.71 | SLC7A5 (0.52) | FOLH1SLC7A5ANPEPENPEPMEP1B | |
| SCHEMBL27752467 | 0.70 | FOLH1 (0.58) | FOLH1ANPEPENPEPMEP1B | |
| SCHEMBL2664262 | 0.70 | MEP1B (0.60) | FOLH1NR1H4MEP1B | |
| SCHEMBL3528768 | 0.70 | SLC7A5 (0.68) | FOLH1SLC7A5ANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102884049-B | Heterocyclic amides useful as ROCK inhibitors | 阿玛克姆股份有限公司 | 2016-08-24 | — | — | CN | disclosed |