Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | TDP2 | O95551 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | ICMT | O60725 | 2/20 | 0.30 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303775 | 0.90 | RARG (0.33) | TRPV4ARTDP2ICMT | |
| SCHEMBL29447080 | 0.90 | TRPV4 (0.36) | TRPV4XDHARTDP2USP2 | |
| SCHEMBL22323989 | 0.90 | TRPV4 (0.36) | TRPV4XDHARTDP2USP2 | |
| SCHEMBL30526793 | 0.86 | TRPV4 (0.47) | TRPV4TDP2USP2MAPTESR2 | |
| SCHEMBL1303773 | 0.86 | TRPV4 (0.30) | TRPV4ESR2 | |
| SCHEMBL1303766 | 0.85 | AR (0.42) | ARUSP2MAPTEGFRSLC6A4 | |
| SCHEMBL30083309 | 0.85 | AR (0.42) | ARUSP2MAPTEGFRSLC6A4 | |
| SCHEMBL28833252 | 0.83 | USP2 (0.30) | USP2MAPT | |
| SCHEMBL28691150 | 0.83 | TRPV4 (0.33) | TRPV4 | |
| SCHEMBL22320285 | 0.81 | ACHE (0.33) | USP2MAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114981251-A | Diphenyl furan derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |