Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19087000 | 0.88 | CSF1R (0.34) | ACHEHIF1AEGFRCSF1RALDH1A1 | |
| SCHEMBL14315050 | 0.86 | L3MBTL1 (0.40) | ALDH1A1MEN1KMT2AL3MBTL1USP2 | |
| SCHEMBL31651983 | 0.84 | LPL (0.40) | EGFRLPLLIPG | |
| SCHEMBL22320292 | 0.83 | PTGDR2 (0.35) | EGFRALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL15454943 | 0.83 | ACHE (0.47) | ACHEEGFRCSF1RALDH1A1MEN1 | |
| SCHEMBL23693218 | 0.82 | FDPS (0.42) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL15940742 | 0.82 | LPL (0.34) | ACHEHIF1AEGFRPOLBUCHL1 | |
| SCHEMBL28833338 | 0.81 | TRPV4 (0.34) | EGFRUSP2MAPT | |
| SCHEMBL4259193 | 0.80 | LPL (0.38) | EGFRLPLLIPG | |
| SCHEMBL29605546 | 0.80 | LPL (0.38) | EGFRLPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924395-A1 | B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2021-12-22 | — | — | EP | disclosed |
| US-11203654-B2 | Bis(aryl phenolate) lewis base catalysts and methods thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-12-21 | — | — | US | disclosed |
| CN-113423742-A | Bis (arylphenolate) lewis base catalysts and processes thereof | 埃克森美孚化学专利公司 | 2021-09-21 | — | — | CN | disclosed |
| WO-2021147882-A1 | DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2021-07-29 | — | — | WO | disclosed |
| WO-2020167824-A1 | B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-08-20 | — | — | WO | disclosed |
| US-20200254431-A1 | BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11203654-B2 | Bis(aryl phenolate) lewis base catalysts and methods thereof | PHKB, TYR, ELL | ACHE 1582/4885HIF1A 4138/4885EGFR 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.