SCHEMBL28833587

SCHEMBL28833587

Fc1cc(C(F)(F)F)n[nH]1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
CHKA P35790 1/20 0.32
IDO1 P14902 1/20 0.31
TRPA1 O75762 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179529 0.78 HPGD (0.44)
SCHEMBL15375205 0.77 CA2 (0.33) CA2CHKAIDO1HSP90AA1HSP90AB1
SCHEMBL20108 0.75 ALOX15 (0.43) CA2CHKAIDO1HSP90AA1HSP90AB1
SCHEMBL30442982 0.75 ALOX15 (0.43) CA2CHKAIDO1HSP90AA1HSP90AB1
Lithium SCHEMBL31258223 0.73 ALOX15 (0.42) CA2CHKAIDO1
SCHEMBL1196699 0.73 CA2 (0.31) CA2CHKAIDO1
SCHEMBL3693279 0.73 NT5E (0.32) CA2CHKAIDO1
SCHEMBL192831 0.73 DHODH (0.44) TRPA1HSP90AA1HSP90AB1
SCHEMBL1461090 0.73 MAPK1 (0.34) CA2CHKAIDO1
SCHEMBL237855 0.73 CA2 (0.40) CA2CHKAIDO1HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105934429-A Process for preparing 5-fluoro-1H-pyrazoles 拜耳作物科学股份公司 2016-09-07 CN disclosed