SCHEMBL15375205

SCHEMBL15375205

FC(F)(F)c1cc(-c2cc(C(F)(F)F)n[nH]2)[nH]n1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
CHKA P35790 1/20 0.33
IDO1 P14902 1/20 0.32
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
TRPV4 Q9HBA0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16743581 0.87 HSP90AA1 (0.37) HSP90AA1HSP90AB1
SCHEMBL16691670 0.81 IDO1 (0.36) CA2CHKAIDO1
SCHEMBL14624000 0.81 RAB9A (0.55)
SCHEMBL4744555 0.80 KIF11 (0.44) IDO1
SCHEMBL18674809 0.80 CA2 (0.33) CA2CHKAIDO1
SCHEMBL863740 0.80 NOTUM (0.36) IDO1
SCHEMBL6331111 0.80 AXL (0.54)
SCHEMBL13024368 0.80 TNIK (0.47)
SCHEMBL5352040 0.78 SMN1; SMN2 (0.56)
SCHEMBL22353107 0.78 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10184052-B2 Near infrared radiation-absorbing composition, near infrared radiation cut-off filter and production method therefor, and camera module and production method therefor FUJIFILM CORPORATION (JP) 2019-01-22 US disclosed
US-10170709-B2 Platinum complex having carbene fragment, OLED using the same, and nitrogen-containing heterocyclic bidentate chelate having carbene unit NATIONAL TSING HUA UNIVERSITY (TW) 2019-01-01 US disclosed
US-10170709-B2 Platinum complex having carbene fragment, OLED using the same, and nitrogen-containing heterocyclic bidentate chelate having carbene unit NATIONAL TSING HUA UNIVERSITY (TW) 2019-01-01 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170005279-A1 PLATINUM COMPLEX HAVING CARBENE FRAGMENT, OLED USING THE SAME, AND NITROGEN-CONTAINING HETEROCYCLIC BIDENTATE CHELATE HAVING CARBENE UNIT NATIONAL TSING HUA UNIVERSITY (TW) 2017-01-05 US disclosed
US-20170005279-A1 PLATINUM COMPLEX HAVING CARBENE FRAGMENT, OLED USING THE SAME, AND NITROGEN-CONTAINING HETEROCYCLIC BIDENTATE CHELATE HAVING CARBENE UNIT NATIONAL TSING HUA UNIVERSITY (TW) 2017-01-05 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
US-9040702-B1 Luminescent platinum(II) complexes with biazolate chelates NATIONAL TSING HUA UNIVERSITY (TW) 2015-05-26 US disclosed
US-8957208-B1 Heteroleptic iridium complex bearing diazolate chelate NATIONAL TSING HUA UNIVERSITY (TW) 2015-02-17 US disclosed
US-8889872-B2 Bisazole-based compound and group VIII transition metal complex NATIONAL TSING HUA UNIVERSITY (TW) 2014-11-18 US disclosed
US-20130296567-A1 BISAZOLE-BASED COMPOUND AND GROUP VIII TRANSITION METAL COMPLEX NATIONAL TSING HUA UNIVERSITY (TW) 2013-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130296567-A1 BISAZOLE-BASED COMPOUND AND GROUP VIII TRANSITION METAL COMPLEX LAS1L, MLKL, HBS1L CA2 602/4885CHKA 2867/4885IDO1 1752/4885
US-20170005279-A1 PLATINUM COMPLEX HAVING CARBENE FRAGMENT, OLED USING THE SAME, AND NITROGEN-CONTAINING HETEROCYCLIC BIDENTATE CHELATE HAVING CARBENE UNIT OCIAD1, OCIAD2, POF1B CA2 1405/4885CHKA 3861/4885IDO1 297/4885
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 CA2 3520/4885CHKA 3379/4885IDO1 2356/4885
US-10170709-B2 Platinum complex having carbene fragment, OLED using the same, and nitrogen-containing heterocyclic bidentate chelate having carbene unit OCIAD1, OCIAD2, POF1B CA2 1405/4885CHKA 3861/4885IDO1 297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.