Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.50 |
| ▸ | CCR2 | P41597 | 5/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295066 | 0.82 | ALDH1A1 (0.47) | POLBALDH1A1KDM4E | |
| SCHEMBL23159509 | 0.80 | CCR2 (0.36) | GPR35CCR2FDPSPOLBALDH1A1 | |
| SCHEMBL23159520 | 0.79 | NOTUM (0.41) | GPR35CCR2FDPSPOLBALDH1A1 | |
| SCHEMBL3762629 | 0.74 | GPR35 (0.50) | GPR35POLBALDH1A1 | |
| SCHEMBL21295045 | 0.73 | CYP2A6 (0.36) | — | |
| SCHEMBL21295039 | 0.73 | — | — | |
| SCHEMBL30067600 | 0.70 | CCR2 (0.69) | GPR35CCR2FDPSPOLBALDH1A1 | |
| SCHEMBL701976 | 0.70 | CCR2 (0.69) | GPR35CCR2FDPSPOLBALDH1A1 | |
| SCHEMBL23159699 | 0.68 | ALDH1A1 (0.46) | POLBALDH1A1KDM4EHPGD | |
| SCHEMBL9613337 | 0.68 | GPR35 (0.62) | GPR35CCR2POLBALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194770-B | Peptidyl arginine deiminase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-08-09 | — | — | CN | disclosed |